The PRR Signalings category encompasses key Pattern Recognition Receptors (PRRs) and their associated signaling pathway components within the innate immune system, including Dectin, NOD1, NOD2, STING, as well as TLR2, TLR3, TLR4, TLR5, TLR7, TLR8, and TLR9. These receptors specifically recognize Pathogen-Associated Molecular Patterns (PAMPs) or Damage-Associated Molecular Patterns (DAMPs), thereby initiating downstream signaling cascades that induce the production of inflammatory cytokines, chemokines, and Type I interferons; they serve as a critical bridge connecting innate immunity with adaptive immunity.
