DRD2

Dopamine is a major catecholamine neurotransmitter that binds dopamine receptors to mediate physiological functions in the central nervous system, including sleep, working memory, emotion and learning. DRD2(S) is a Gi-coupled D2-like dopamine receptor, whose activation suppresses adenylyl cyclase and reduces intracellular cAMP, serving as a key target for CNS disorder drug discovery. Our DRD2(S) stable CHO-K1 cell lines have been validated in cAMP assays to support your drug discovery programs.