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CCR9 (chemokine receptor 9) is a G protein-coupled receptor expressed on immature T lymphocytes and intestinal cells. Its endogenous ligand CCL25 activates Gi signaling, leading to reduced intracellular cAMP. CCR9 participates in lymphocyte homing and serves as a potential biomarker and therapeutic target for multiple cancers. Our CCR9 stable CHO-K1 cell lines have been validated in cAMP assays to support your drug discovery programs.