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Drug Target Models

GPCR Reporter Cells

Class B2（Adhesion） Class A（Rhodopsin） Class B1（Secretin） Class C（Glutamate） Combination Orphan and other 7TM Parental Cell

Immunotherapy cells

Fc Effector Combination T Cell Activation Co-Stimulatory Co-Inhibitory Immune Checkpoint Cytokine&Growth Factor TAA Other PRR

Other Stable Cells

Signaling pathway cells Tracer Cell Nuclear Receptor Ion Channel Transporter Other

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Home>Drug Target Models>Class A（Rhodopsin）
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GPCR Reporter Cells
Class A（Rhodopsin） Class B1（Secretin） Class C（Glutamate） Combination Orphan and other 7TM Parental Cell Class B2（Adhesion）
Immunotherapy cells
Combination Fc Effector T Cell Activation Co-Stimulatory Co-Inhibitory Immune Checkpoint Cytokine&Growth Factor TAA Other PRR
Other Stable Cells
Signaling pathway cells Tracer Cell Nuclear Receptor Ion Channel Transporter Other
Assay Kits & Reagents
Assay Kits Reagents

CXCR1

CXCR1 is a GPCR mainly expressed on immune cells. IL-8 and GCP-2 binding activates Gαi, inhibiting adenylate cyclase and reducing intracellular cAMP. It mediates inflammatory responses, closely involved in rheumatoid arthritis, pneumonia, breast cancer and pancreatic cancer, and serves as a key drug target for inflammatory diseases and tumors. Our CXCR1 stable CHO-K1 cell lines have been validated in cAMP assays to support your drug discovery programs.

Item number
Cell name
Details
RQP71660 CHO-K1 Rat CXCR1 Cell Line Query RQP71410 CHO-K1 Human CXCR1 β-Arrestin Cell Line Query RQP71360 CHO-K1 Human CXCR1 Cell Line Query
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