GPR35

GPR35 is a protein‑coding gene belonging to the G protein‑coupled receptor (GPCR) family, classified as Class A rhodopsin‑like receptor. Its endogenous ligands such as kynurenic acid activate Gi/o and G13 signaling, exerting context‑dependent dual roles in immune defense and inflammatory regulation. Diseases associated with GPR35 include inflammatory bowel disease, type 2 diabetes, coronary artery disease and gastric cancer. Our GPR35 stable cell lines have been validated in functional assays to support your drug discovery programs.