Home>Drug Target Models>Class A(Rhodopsin)

GPR1

GPR1 is a GPCR expressed in the hippocampus, adipose tissue and multiple organs, which binds chemerin as its primary ligand. It regulates lipid metabolism, glucose homeostasis and inflammatory responses, and also acts as a co-receptor for HIV entry. GPR1 is closely associated with obesity, diabetes, PCOS and multiple cancers, emerging as a promising therapeutic target for metabolic disorders. Our GPR1 β-Arrestin CHO-K1 cell lines have been validated in β-arrestin recruitment assays to support your drug discovery programs.

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