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The Role of the CCL2-CCR2 Axis in Cancer Immunity

From Inflammation to Cancer: Biological Functions of the CCL2-CCR2 Axis and New Progress in Targeted Drug R&D

As our understanding of the tumor microenvironment deepens, targeting the CCL2-CCR2 axis is transitioning from concept to clinical reality. Whether you are developing small molecule inhibitors, neutralizing antibodies, or novel ADCs, reliable screening models are the cornerstone of success. Reqbio remains committed to focusing on frontier targets in GPCRs and immuno-oncology, providing high-quality biological reagents and cell models to empower global innovative drug discovery.

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Unlocking the Dual Potential of ICOS: The Next Frontier in Immuno-Oncology and ICOS (CD278) Cell Model Solutions

Unlocking the Dual Potential of ICOS: The Next Frontier in Immuno-Oncology and ICOS (CD278) Cell Model Solutions

With the deepening understanding of ICOS biology and the optimization of combination therapy strategies, this target holds great promise for the development of breakthrough therapeutics in the near future. Renkun Biotech remains committed to providing high-quality biological reagents and cell models to empower innovative drug discovery worldwide. Whether you are developing novel ICOS antibodies or exploring combination therapies, our tools are designed to accelerate your research from the lab to the clinic.

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 Inhibition of Human IL17A induced Reporter Activity by IL17RA Blocking or IL17A Neutralization Ab in IL17A/17F Effector Reporter Cell(C45).

Focusing on the IL-17 Target: The "Golden Track" of Autoimmune Drug R&D and Essential Tool Models

ReqBio remains committed to the frontiers of immunotherapy, providing high-quality biological reagents and cell models to help global researchers conquer autoimmune diseases.

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Dose Response of Tebentafusp (IMCgp100) in NFAT-Luc Jurkat(C7C17) with or without GP100(YLEPGPVTA) HLA0201 CHO.

NFAT Signaling Pathway: A Critical Target for Drug R&D and Cell Models

Reqbio provides professional NFAT signaling pathway research solutions, featuring functionally validated NFAT-Luc reporter gene cell models (Jurkat, HEK293, THP-1, CHO). Our cell models are ideal tools for screening NFAT inhibitors (such as Cyclosporine A), developing immunotherapies, and studying the mechanisms of cancer and autoimmune diseases. Covering NFAT1-5 targets, our products facilitate target validation and high-throughput drug screening.

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HEK293 Human TSHR CRE-Luc Cell Line

TSHR Cell Model for Thyroid Cancer Drug Screening | GPCR Assay Platform-Reqbio

Reqbio provides professional TSHR cell models (CRE-Luc HEK293/CHO) for thyroid cancer targeted drug screening, GPCR signaling research, and reporter gene assays. Explore 1500+ ready-to-use models for drug R&D and bioassay services.

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HTRF cAMP Assay with MC4R CHO (C9)-Reqbio

MC4R – A Niche Target in Weight Loss

MC4R (melanocortin 4 receptor) is a member of the melanocortin receptor family, which belongs to the rhodopsin-like class A GPCR family.

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