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PTGIR

PTGIR is a receptor for prostacyclin (PGI2), widely expressed in the brain, placenta, blood vessels and peripheral tissues. Activation of PTGIR mediates Gαs-cAMP downstream signaling, regulating vasodilation, platelet aggregation and immune function. PTGIR is an important target for cardiovascular and oncology drug discovery. Our PTGIR stable cell lines are validated for cAMP assays to support your drug discovery programs.

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