GLP1R GCGR GIPR

GLP1R, GCGR and GIPR are receptors for GLP‑1, glucagon and GIP, critical modulators of glucose and energy metabolism. Activation of GLP1R, GCGR and GIPR elevates intracellular cAMP concentration. GLP1R/GCGR/GIPR triple agonists deliver synergistic benefits for glycemic control and weight reduction, representing a promising strategy for obesity and T2DM treatment. Our GLP1R GCGR GIPR triple reporter stable cell lines are validated for cAMP reporter assays to support your drug discovery programs.