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EDNRB (Endothelin Receptor Type B) is a class A GPCR that binds endothelin ligands. It mediates diverse physiological processes including vascular homeostasis, melanocyte development and neural crest cell migration, and is associated with Waardenburg Syndrome Type 4A and other disorders, serving as an important therapeutic target. Our EDNRB stable CHO-K1 cell lines have been validated in Gq signaling assays to support your drug discovery programs.